Squarize Lab

The University of Michigan School of Dentistry

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ABOUT


We are determined to understand the function of the key signaling molecules and stem cells in epithelial regeneration and disease.

Our research uses cutting edge technology, combined with the use of in vitro studies and preclinical in vivo models, to solve critical clinical questions and problems related to healing of the oral mucosa and skin, as well as epithelial cancer progression and resistance to therapy.

CANCER (HNSCC)

cancer hnscc
Pullos & Squarize, JDR
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STEM CELL (EPITHELIAL)

stem cell
Squarize lab data
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TISSUE REGENERATION (STEM CELL - MUCOSA/SKIN)

tissue regeneration
Squarize et al, PLoSOne

DIRECTOR

Cristiane H. Squarize

Cristiane H. Squarize, DDS, MS, PhD
Associate Professor of Dentistry

csquariz@umich.edu | 734-615-3406

Dr. Squarize is an Associate Professor with tenure and Principal Investigator of the Epithelial Biology Lab at the UM. She earned a DDS, followed by a Master’s degree and PhD in Oral Pathology. She won the prestigious Edward Hatton Award from the International Association for Dental Research for her head and neck cancer research. Before joining the University of Michigan in 2010, she completed her training and service on surgical and experimental pathology, followed by a five years fellowship at the National Institute of Dental and Craniofacial Research, focusing on Stem Cell Biology and Epithelial Biology, as well as Oral and Pharyngeal Cancer. Dr. Squarize is also a member of the Michigan Medicine Rogel Cancer Center and the Division Leader on the UM SoD Global Initiative.

Dr. Squarize established national and international collaborations to advance science and has mentored students from diverse backgrounds. The students in her laboratory are from many academic majors, including chemistry, biology, pharmacy, dentistry, medicine, computational science, among others. This interdisciplinary group of students and professionals works together towards the identification of solutions and novel treatments for epithelial cancers, and the promotion of regeneration of mucosa and skin.

PUBLICATIONS

SCIENTIFIC JOURNAL COVERS

cancer research cover
neoplasia cover
oral surgery cover
oral surgery cover
umich cover

BOOKS AND BOOK CHAPTERS

  • Cristiane H. Squarize and Rogerio M. Castilho. Emerging animal models. Current Methods in Medicinal Chemistry and Biological Physics. Edited by Carlton A. Taft , Carlos H. T. P. Silva. Research Signpost 207-226, 2007. ISBN: 81-308-0141-8
  • Cristiane H. Squarize, Rogerio M. Castilho and Andreia M. Leopoldino. Drug Target Validation. Current Methods in Medicinal Chemistry and Biological Physics. Vol. 2. Edited by Carlton A. Taft, Carlos H. T. P. Silva. Research Signpost 167-186, 2008. ISBN: 978-81-308-0292-3

The most recent publications are reported below.

View the complete list of publications

LAB TEAM

Cristiane H. Squarize

Cristiane H. Squarize, DDS, MS, PhD
Principal Investigator

Liana Preto Webber, DDS, MS

Liana Preto Webber, DDS, MS
Visiting Scholar, PhD Candidate

Ana Elizia Mascarenhas, DDS, MS

Ana Elizia Mascarenhas, DDS, MS
PhD Candidate

Veronica Yujra DDS, MS

Veronica Yujra DDS, MS
PhD Candidate

Thamara Bezerra DDS, MS

Thamara Bezerra DDS, MS
PhD Candidate

Ericka J.D. Silveira

Ericka J.D. Silveira
Visiting Scholar

Marisol Miranda Galvis, DDS, MS

Marisol Miranda Galvis, DDS, MS
Visiting Scholar

LAB ALUMNI

Luciana O. Almeida, PhD
lucianao@umich.edu

Gabriel A. Borges
galvares@umich.edu

Carolina Siviero Dillenburg, DDS, MS
carolsd@gmail.com

Maria José Fernandez, DDS, PhD
mariajosefernandez_75@hotmail.com

Fernanda Giudice, DDS, MS
fernandagiudice@yahoo.com.br

John M. Le, DDS
johnmle@umich.edu

Manoela Domingues Martins, DDS, MS, PhD
manomartins@gmail.com

Marco Antonio Trevizani Martins, DDS, MS, PhD
marcotm@umich.edu

Camila Matsumoto, PhD
camilasm.85@gmail.com

Alissa Pullos, DDS
alissa.pullos@uc.edu

Glaucia Soares, DDS, MS

Vivian Petersen Wager, DDS, MS
petersev@umich.edu

Brian Yip, DDS
brianyip@umich.edu

Chiara Zagni, PhD
uchiacch@unict.it

CONTACT

Squarize Lab
University of Michigan School of Dentistry
1011 N University Ave, Room 6218
Ann Arbor, MI 48109
734-615-3406 | csquariz@umich.edu
cristiane squarize at computer