The University of Michigan School of Dentistry
The mouth provides us with remarkable sensations.
We bite into, adeptly manipulate, and crunch foods without inflicting self-injury. Our dentition and supporting structures routinely tolerate extreme forces of mastication, yet they also allow us to discern minuscule changes in bite and unanticipated hard particulates in food. We hardly notice these forces in normal chewing function; however, if the teeth are damaged and the dental pulps become inflamed, their sensory input is altered and we begin to experience excruciating pain – the toothache.
In thinking about these phenomena, we also wonder: What makes the tongue and lips profoundly sensitive to touch? How do common components (i.e., sensory neurons) provide us with unique sensations from distinct tissues? What makes our mouth feel dry? Why is tooth pain exquisite? And how do we inherently “know” the position of our teeth, jaws, and tongue when we eat and speak?
The Emrick lab is interested in answering these types of questions (and others) by studying the molecules, cells, and circuitry of the sensory nervous system innervating the mouth, head, and neck. To this end we use a number of state-of-the-art techniques to study trigeminal somatosensory neurons including 1) multiround, multiplex in situ hybridization and machine learning algorithm-guided transcriptional classification, 2) viral and genetic approaches for tracing connectivity and manipulating function using opto-/chemogenetics, and 3) an in vivo imaging platform to monitor responses to oral tissue stimulation at single-cell resolution. Above all, we want to understand how the sensory nervous system encodes oral and craniofacial information, contributes to normal tissue function, and ultimately drives reflexes and perceptions.
Dr. Joshua Emrick is an assistant professor in the Department of Biologic and Materials Sciences & Prosthodontics at the University of Michigan School of Dentistry. He was awarded his D.D.S. and Ph.D. in oral and craniofacial biology from the University of California - San Francisco School of Dentistry, completing his dissertation with Dr. David Julius (Nobel Prize, 2021). Prior to joining Michigan, Dr. Emrick conducted his postdoctoral studies as a Dental Clinical Research Fellow at the National Institute of Dental and Craniofacial Research (NIDCR) with Dr. Nicholas Ryba.
Dr. Emrick is a U-M Biological Sciences Scholar (2021) and Kavli Fellow of the National Academy of Sciences (2024). He is a native Michigander from Flint. In his free time he enjoys being outdoors with his wife and two daughters, and brewing his own beer.
The Emrick lab is actively recruiting members to join our budding research group on Central Campus.
Importantly, lab members are expected contribute to a culture that embraces curiosity, integrity, excitement, respect, and cooperation. We will do our best to enjoy working hard together.
If you are excited about joining our group, please contact Dr. Joshua Emrick ([email protected]) with an up-to-date CV as well as a cover letter describing your research interest, relevant experience, and career goals. Feel free to forward as appropriate.
Postdoctoral Fellow
B.S. Neuroscience, University of Michigan
M.S. Molecular and Integrative Physiology, University of Michigan
Ph.D. Molecular and Integrative Physiology, University of Michigan, 2022
Email: [email protected]
Hometown: Royal Oak, Michigan
Interests:My research broadly aims to understand how animals sense their external world to produce behavioral outputs. Currently, I am focused on uncovering the neural and molecular mechanisms by which structures within the oral cavity detect and transduce various sensory cues, including touch, temperature, and pain.
Oral Health Sciences, DDS/PhD Student
B.S. Genetics and Developmental Biology, Cornell University, 2020
Email: [email protected]
Hometown: Blauvelt, NY
Interests: I am interested in sensory neuroscience and the interpretation of pain. My current research project is about elucidating the innervation of the temporomandibular joint and understanding how these neurons play a role in chronic pain. In my free time, you can find me cycling (both indoor and outdoor), long walks with my dog, or trying to make new recipes.
Neuroscience PhD Student
B.S. Neuroscience, Bucknell University, 2021
Email: [email protected]
Hometown: Pequannock, NJ
Interests: I am broadly interested in sensory neuroscience and neuroimmunology. My current research is focused on mapping the sensory neurons that innervate the salivary glands and understanding how these neurons may regulate saliva production and composition. Outside of the lab, you can find me hiking with my dog, reading sci-fi/fantasy, playing Zelda, or tap dancing.
Research Lab Technician
B.S. Biopsychology, Cognition, and Neuroscience, University of Michigan, 2024
Email: [email protected]
Hometown: Escanaba, MI
Interests: I am broadly interested in molecular neuroscience and how our craniofacial research relates to real-life medical applications. After exploring research, I plan to pursue my interests by attending dental school. Outside of the lab, I enjoy exercising, reading, playing tennis, and 3D printing.
Lab Manager, Research Lab Specialist
B.S. Neuroscience, Michigan State University, 2023
Email: [email protected]
Hometown: Canton, MI
Interests: I am an aspiring dental student with a broad interest in Neuroscience, particularly in the mechanisms of innervation within the oral cavity. I hope to deepen my understanding of the dental field through the lens of research. When I'm not working, I enjoy creating art, going on walks, and reading.
Research Investigator
B.S. Biology, Tunghai University, Taiwan
Ph.D. Life Science, Tunghai University, Taiwan
Email: [email protected]
Hometown: Hsinchu, Taiwan
Interests: I am interested in metabolism and lipid homeostasis in neuroscience. Currently, I am trying to tackle the questions of how the pain interacts with reflex. When I have free time, I like exploring nature and baking chiffon cakes.
Undergraduate Student
B.S.E. Biomedical Engineering, University of Michigan, Expected 2025
Email: [email protected]
Hometown: Louisville, KY
Interests: I’m interested in the intersection of tissue engineering and traditional dentistry; I enjoy learning about the computational side of research. I hope to attend dental school in the future to pursue this in practice. Outside of the lab, you’ll find me tinkering with med devices, rollerblading, painting, and reading.
Neuroscience PhD Student
B.S. Genetics & Biotechnology and B.A. Philosophy, New Mexico State University, 2023
Email: [email protected]
Hometown: Rio Rancho, NM
Interests: I am interested in understanding how animals modulate behavioral outputs in response to sensory information. In the lab, I hope to understand how sensation in the tooth alters behavioral responses in mice by using ethologically relevant behavioral paradigms and physiological measures. Outside of the lab, I enjoy playing with my cat Dewey (whose behavior I will never understand), watching Breaking Bad, golfing, and exploring the outdoors.
Undergraduate Student
B.S. Biomolecular Sciences
University of Michigan, Expected 2026
Email: [email protected]
Hometown: Dallas, Texas
Interests: I am broadly interested in neuroscience and gaining a better understanding of pain and reflex by mapping sensory neurons. I hope to use my experience and knowledge from the lab to pursue dentistry in the future. . Outside of the lab, I enjoy running, giving tours on campus, and watching movies with friends and family.
Undergraduate Student
B.S. Biomolecular Sciences & B.A. Spanish
University of Michigan, Expected 2026
Email: [email protected]
Hometown: Seoul, South Korea & Jenison, Michigan
Interests: Through the research at the dental school, I hope to gain a deeper understanding of the intricate mechanisms governing the mouth, head, and neck, as well as the connections between the mouth and the brain. In the future, I aspire to attend medical school and use my proficiency in English, Korean, and Spanish to help as many families as possible, ensuring that language barriers do not hinder access to quality care. In my free time, I like playing pickleball, listening to audiobooks, or crocheting with my roommates.
Undergraduate Student
B.S. Chemistry
University of Michigan, Expected 2026
Email: [email protected]
Hometown: Powell, Ohio
Interests: My interests lie in the field of chemistry with expectations to go into the medical field. Currently in the lab, I am working to define how sensory neurons present in the salivary glands affect the composition of saliva output. During my free time, I like to spend my time with family and friends, go to concerts and sporting events, and listen to fun podcasts.
Mechanical Engineering PhD Student
B.S. Mechanical Engineering, University of California, Davis, 2022
B.S. Aerospace Science and Engineering, University of California, Davis, 2022
Email: [email protected]
Hometown: Shanghai, China
Interests: My research focuses on elucidating thermosensation mechanisms within the oral cavity, thereby establishing a foundation for further exploration of thermal therapies in dental applications. I seek to leverage my engineering background to introduce new approaches and insights into dental and neuroscience studies. In my leisure time, I make ship models, play the guitar, and do gardening.
D.D.S., University of Michigan
Expected 2026
Email: [email protected]
Hometown: Lisle, Illinois
Interests:As a dental student, I am interested in understanding the complex mechanisms underlying oral sensation and pain perception. Engaging in research has helped me become a better clinician and problem solver. In my free time, I love to travel and am excited to visit Taiwan and Kenya in the coming year!
Undergraduate Student
B.S. Neuroscience, University of Michigan, Expected 2027
Email: [email protected]
Hometown: Northville, Michigan
Interests:I find myself most intrigued about the brain and how its neural complexity works to impact our behavior on a daily basis. I hope to attend medical school pursuing my interest in neuroscience as well as participate in research along the way! Aside from working in lab, you can find me figure skating, watching new tv shows/movies, building legos, and drinking lots of bubble tea/coffee.
Akash Gandhi
Former Research Lab Technician
Kaitijane Blumberg
Former Research Lab Technician
Seoyoon Chang
Former Undergraduate Research Assistant
Mak Guenther
Former Research Lab Specialist, Lab Manager
Simon Lafleur
Former U-M Life Sciences Institute Perrigo Fellow
Brian Constantinescu
Former Research Lab Technician
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Joshua Emrick is a scientist and dentist with an interest in oral somatosensation, particularly pain.
Read Full ArticleBSSP
The Biological Sciences Scholars Program (BSSP) provides start-up funds to recruit outstanding scientists in key areas of life sciences investigation. The goal of the program is to develop a new generation of leaders in bioscience research at the University of Michigan.
Read Full ArticleEmail: [email protected]
Telephone: (734) 763-1080
Fax: (734) 763-3453
Twitter: @jjemrick