Ritchie Lab

The University of Michigan School of Dentistry

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ABOUT

The Ritchie laboratory is focused on studying two major dentin noncollagenous proteins, dentin sialoprotein (DSP) and physophporyn (PP) which appear to play a significant role in the conversion of uncalcified predentin to calcified dentin.

DIRECTOR

Helena Ritchie, MS, PhD
Associate Professor

helenar@umich.edu | 734-763-3746

Dr. Ritchie is focused on studying two major dentin noncollagenous proteins - dentin sialoprotein (DSP) and physophporyn (PP) - whose appearance is coupled to the conversion of uncalcified predentin to calcified dentin. The work encompassess following four DSP-PP related areas: (1) regulation and function of rat dentin sialoprotein and phosphophoryn, (2) tissue engineering to test whether DSP and PP proteins can serve as biomimetic molecules in promoting dentin regeneration, (3) DSP-PP gene expression in non-mineralized tissues such as bone, kidney and salivary glands during organogenesis, and (4) DSP-PP precursor processing studies.

PUBLICATIONS

The most recent publications are reported below.

View the complete listing of publications.

CONTACT

Ritchie Lab
University of Michigan School of Dentistry
1011 N University Ave,
Ann Arbor, MI 48109