The University of Michigan School of Dentistry
Peter X Ma is the Richard H Kingery Endowed Collegiate Professor of Biologic and Materials Sciences, Biomedical Engineering, Materials Science and Engineering, and Macromolecular Science and Engineering at the University of Michigan. His research is in the areas of biomaterials, biomedical polymers, controlled release, tissue engineering, and regenerative medicine. He pioneers biomimetic scaffold development to design microenvironments for cells and tissue regeneration. He also develops controlled delivery systems for non-viral nucleic acids, peptides, proteins, and small molecules in sustained, pulsatile, and targeted fashions.
Among various recognitions, Dr. Ma received a Whitaker Foundation Biomedical Engineering Young Investigator Award, a DuPont Young Professor Award, a Distinguished Scientist Award (Isaac Schour Memorial Award) from the International Association of Dental Research, and a Clemson Award from the Society for Biomaterials. He was named one of the Top 100 materials scientists in the world by Thomson Reuters. He is an elected Fellow of the American Institute for Medical and Biological Engineering, Fellow of Biomaterials Science and Engineering, Fellow of the Materials Research Society and Fellow of American Association for the Advancement of Science.
Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects
2016; Nature Communications; Zhang, X. | Li, Y. | Chen, Y.E. | Chen, J. | Ma, P.X.
Local pulsatile PTH delivery regenerates bone defects via enhanced bone remodeling in a cell-free scaffold
2016; Biomaterials; Dang M. | Koh A.J. | Jin X. | McCauley L.K. | Ma, P.X.
The most recent publications are reported below.
Macromolecular design and synthesis of biodegradable scaffolds for tissue engineering and microgels for drug delivery.
MicroRNAs to induce the differentiation of cardiac progenitor cells for cardiac regeneration.
Polymer design and synthesis of a conductive hydrogel for tissue engineering.
Peptide-functionalized particle drug delivery strategies to target HER2+ breast cancer cells and regenerate adipose tissue through eventual minimally invasive techniques using the Ma lab's nanofibrous microsphere cell carrier platform for soft tissue defects.
Macrophage-based systems for tissue repair and regeneration. Possible focus on bone and cartilage regeneration.
Sam is developing a Biomimetic scaffold for the regeneration of blood vessels.
Tuned-release delivery system of biologic therapeutics and multi-phasic biodegradable scaffolds for engineered tissue interfaces. Possible applications towards alveolar bone and cranial suture mesenchyme regeneration.
Tubular scaffold used in vascular graft, microspheres for drug delivery.
Biomaterials and mineralization
Inflammatory pulp survival and regeneration
The application of exosomes derived from stem cells for intervertebral disc regeneration
The role of physical properties of biomaterials in the maintenance and regulation of pluripotency of embryonic stem cells
Tubular tissue engineering for blood vessel replacement
Nanomaterials enhanced osteogenic differentiation by TGF-beta/Smad3 signaling pathway. Non-viral vectors to deliver miRNA to osteogenic differentiation.
3D nanofibrous scaffold with stem cells to regenerate articular cartilage.
University of Michigan School of Dentistry
1011 North University
Ann Arbor 48109, MI