Ma Lab

The University of Michigan School of Dentistry

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ABOUT

AREAS OF FOCUS

  1. Bioactive scaffolds for tissue engineering and 3D surface functionalization
  2. Biomimetic Materials: Development of novel synthetic materials inspired by natural materials
  3. Regeneration of 3D functional tissues (bone, cartilage, liver, cardiovascular tissues): understanding polymer-cell interactions and signal and substrate requirements for cell proliferation, differentiation, and tissue regeneration
  4. Controlled Release: Nano/micro-spheres and matrices for the delivery of drugs and biological molecules in a sustained, pulsatile, targeted, or environmentally responsive manner
  5. Phase-separation and Self-assembly: Physical mechanisms and biomedical applications of three-dimensional ordered structure formation, especially at the nanometer scale

DIRECTOR

peter ma

PETER X MA, PhD, FBSE
Principal Investigator

Professor, Schools of Dentistry, Engineering, and Medicine

Peter X Ma is the Richard H Kingery Endowed Collegiate Professor of Biologic and Materials Sciences, Biomedical Engineering, Materials Science and Engineering, and Macromolecular Science and Engineering at the University of Michigan. His research is in the areas of biomaterials, biomedical polymers, controlled release, tissue engineering, and regenerative medicine. He pioneers biomimetic scaffold development to design microenvironments for cells and tissue regeneration. He also develops controlled delivery systems for non-viral nucleic acids, peptides, proteins, and small molecules in sustained, pulsatile, and targeted fashions.

Among various recognitions, Dr. Ma received a Whitaker Foundation Biomedical Engineering Young Investigator Award, a DuPont Young Professor Award, a Distinguished Scientist Award (Isaac Schour Memorial Award) from the International Association of Dental Research, and a Clemson Award from the Society for Biomaterials. He was named one of the Top 100 materials scientists in the world by Thomson Reuters. He is an elected Fellow of the American Institute for Medical and Biological Engineering, Fellow of Biomaterials Science and Engineering, Fellow of the Materials Research Society and Fellow of American Association for the Advancement of Science.

mapx@umich.edu

PUBLICATIONS

FEATURED PUBLICATIONS

Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects
2016; Nature Communications; Zhang, X. | Li, Y. | Chen, Y.E. | Chen, J. | Ma, P.X.

Local pulsatile PTH delivery regenerates bone defects via enhanced bone remodeling in a cell-free scaffold
2016; Biomaterials; Dang M. | Koh A.J. | Jin X. | McCauley L.K. | Ma, P.X.

The most recent publications are reported below.

View the complete listing of publications by Dr. Ma

TEAM

POSTDOCTORAL RESEARCHER(S)

kemao xiu

Kemao Xiu, PhD

Research Specialist
Biologic and Materials Science

Macromolecular design and synthesis of biodegradable scaffolds for tissue engineering and microgels for drug delivery.

ruonan dong

Ruonan Dong, PhD

Research Specialist
Biologic and Materials Science

MicroRNAs to induce the differentiation of cardiac progenitor cells for cardiac regeneration.

semin kim

Semin Kim, PhD

Research Specialist
Biologic and Materials Science

Polymer design and synthesis of a conductive hydrogel for tissue engineering.


DOCTORAL STUDENTS

yasmine doleyres

Yasmine Doleyres

PhD Candidate
Macromolecular Science and Engineering

Peptide-functionalized particle drug delivery strategies to target HER2+ breast cancer cells and regenerate adipose tissue through eventual minimally invasive techniques using the Ma lab's nanofibrous microsphere cell carrier platform for soft tissue defects.

raha kannan

Raha Kannan

PhD Candidate
Biomedical Engineering

Macrophage-based systems for tissue repair and regeneration. Possible focus on bone and cartilage regeneration.

sam renato navarro

Sam (Renato) Navarro

PhD Candidate
Macromolecular Science and Engineering

Sam is developing a Biomimetic scaffold for the regeneration of blood vessels.

ben swanson

W. Benton Swanson

DDS/PhD Candidate
Oral Health Sciences DDS/PhD

Tuned-release delivery system of biologic therapeutics and multi-phasic biodegradable scaffolds for engineered tissue interfaces. Possible applications towards alveolar bone and cranial suture mesenchyme regeneration.

tongqing zhou

Tongqing Zhou

PhD Pre-Candidate

Tubular scaffold used in vascular graft, microspheres for drug delivery.


VISITING SCHOLARS

tianming du

Tianming Du

Visiting Scholar

Biomaterials and mineralization

weiyu gong

Weiyu Gong, DDS, MD

Visiting Scholar

Inflammatory pulp survival and regeneration

ming guan

Ming Guan, MD (PhD Candidate)

Visiting Scholar

The application of exosomes derived from stem cells for intervertebral disc regeneration

youlong xie

Youlong Xie, PhD

Visiting Scholar

The role of physical properties of biomaterials in the maintenance and regulation of pluripotency of embryonic stem cells

yuwei xiang

Yuwei Xiang, MD

Visiting Scholar

Tubular tissue engineering for blood vessel replacement

yi guo

Yi Guo

Visiting Scholar

Nanomaterials enhanced osteogenic differentiation by TGF-beta/Smad3 signaling pathway. Non-viral vectors to deliver miRNA to osteogenic differentiation.

li chen

Li Chen, MD

Visiting Scholar

3D nanofibrous scaffold with stem cells to regenerate articular cartilage.

CONTACT

Ma Lab
University of Michigan School of Dentistry
Room 2211
1011 North University
Ann Arbor 48109, MI

Phone: 734-764-2209
Email: mapx@umich.edu