Professor, Schools of Dentistry, Engineering, and Medicine
Peter X Ma is the Richard H Kingery Endowed Collegiate Professor of Biologic and Materials Sciences, Biomedical Engineering, Materials Science and Engineering, and Macromolecular Science and Engineering at the University of Michigan. His research is in the areas of biomaterials, biomedical polymers, controlled release, tissue engineering, and regenerative medicine. He pioneers biomimetic scaffold development to design microenvironments for cells and tissue regeneration. He also develops controlled delivery systems for non-viral nucleic acids, peptides, proteins, and small molecules in sustained, pulsatile, and targeted fashions.
Among various recognitions, Dr. Ma received a Whitaker Foundation Biomedical Engineering Young Investigator Award, a DuPont Young Professor Award, a Distinguished Scientist Award (Isaac Schour Memorial Award) from the International Association of Dental Research, and a Clemson Award from the Society for Biomaterials. He was named one of the Top 100 materials scientists in the world by Thomson Reuters. He is an elected Fellow of the American Institute for Medical and Biological Engineering, Fellow of Biomaterials Science and Engineering, Fellow of the Materials Research Society and Fellow of American Association for the Advancement of Science.
Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects
2016; Nature Communications; Zhang, X. | Li, Y. | Chen, Y.E. | Chen, J. | Ma, P.X.
Local pulsatile PTH delivery regenerates bone defects via enhanced bone remodeling in a cell-free scaffold
2016; Biomaterials; Dang M. | Koh A.J. | Jin X. | McCauley L.K. | Ma, P.X.
Stem cell-based bone repair and cartilage regeneration, investigating the function of macrophages in bone repair.
MicroRNAs to induce the differentiation of cardiac progenitor cells for cardiac regeneration.
Construction of thermo-responsive drug delivery system and dual delivery systems for bone tissue engineering.
Investigating the effect of material architecture on cell phenotype turnover, specifically focused on the stem cell lineage differentiation.
Development of hydrogels for tissue engineering and novel microgels for drug delivery.
Intervertebral disc and cartilage regeneration.
Preprogrammed drug delivery device for osteoporosis treatment and bone regeneration, stimuli-responsive hydrogel, and biomimetic approaches in bone regeneration.
Peptide-functionalized particle drug delivery strategies to target HER2+ breast cancer cells and regenerate adipose tissue through eventual minimally invasive techniques using the Ma lab's nanofibrous microsphere cell carrier platform for soft tissue defects.
Sam is developing a Biomimetic scaffold for the regeneration of blood vessels.
Regeneration of critical size bone defects using nanofibrous spongy microspheres developed in the Ma Lab and a dual drug delivery platform.
Polymeric vectors for delivery of nucleotides based on a two-stage system developed in the Ma Lab. Possible applications include delivery of miRNA in therapy for breast cancer and fibrosis.